Advise patients to notify their healthcare provider if they become pregnant or intend to become pregnant during treatment with RISPERDAL. Advise patients that RISPERDAL may cause extrapyramidal and/or withdrawal symptoms in a neonate. Advise patients that there is a pregnancy registry that monitors pregnancy outcomes in women exposed to RISPERDAL during pregnancy see Use In Specific Populations.
Administration Of RISPERDAL Oral Solution
Many other medicines may alter the blood levels of Uzedy. Tell your healthcare provider about all medicines that you take or have recently taken. Uzedy can affect your ability to regulate your body temperature. This could make you become very hot, especially in hot weather or after exercising a lot.
Uzedy
- If someone has collapsed, is unconscious, has a seizure, or has problems breathing after taking risperidone, immediately call 911 for emergency services.
- Other adverse reactions reported since market introduction related to RISPERDAL overdose include prolonged QT interval and convulsions.
- There are reports of sedation, failure to thrive, jitteriness, and extrapyramidal symptoms (tremors and abnormal muscle movements) in breastfed infants exposed to risperidone (see Clinical Considerations).
- In healthy elderly subjects, renal clearance of both risperidone and 9-hydroxyrisperidone was decreased, and elimination half-lives were prolonged compared to young healthy subjects.
Get your prescription refilled before you run out of medicine completely. Follow all directions on your prescription risperidone risperdal: uses, interactions and side effects label and read all medication guides or instruction sheets. Risperidone may temporarily affect fertility (ability to have children) in women. Risperdal is also used to treat symptoms of irritability in autistic children who are 5 to 16 years old.
Drug Categories
Although there are no mandatory requirements for therapeutic drug monitoring with risperidone, monitoring plasma concentrations for this medication is strongly recommended by European guidelines because of data showing interdependent variability. Therapeutic monitoring can benefit from assessing compliance and identifying low drug concentrations that may be low, resulting in therapeutic failure. Also, monitoring the drug level can aid in evaluating potential drug interactions and adverse effects. Although these adverse effects are thought to be reversible, the duration of Parkinsonian features after discontinuation of the medication can vary. Tardive dyskinesia, however, will likely persist after the medication is discontinued and may be permanent. In addition to discontinuation of the antipsychotic, pharmacologic treatments are available that may help with certain extrapyramidal symptoms.1718 One potential adverse effect of risperidone is orthostatic hypotension.
Who should not use Uzedy?
Tell your health care provider right away if you have any of the following symptoms of orthostatic hypotension. Risperidone can cause high blood sugar levels or diabetes, high cholesterol levels, and weight gain. Keep all appointments with your health care provider to check your blood work and weight. Call your health care provider if you gain weight or develop the following symptoms of high blood sugar. The most common side effects of risperidone are listed below. These side effects may vary based on the condition being treated and the dosage form you are using.
The extended-release intramuscular formulation is available in 12.5 mg, 25 mg, 37.5 mg, and 50 mg doses. A prefilled syringe for subcutaneous administration is available in 90 mg and 120 mg solutions. Subcutaneous syringes containing 50 mg, 75 mg, 100mg, 125 mg, 150 mg, 175 mg, 200 mg, and 250 mg doses are also available.
This will help them determine if risperidone is right for you. If you are prescribed risperidone orally disintegrating tablets, do not remove the tablet from its blister pack until you are ready to take it. You should peel back the foil to open the blister pack. Do not push the tablet through the foil because doing so could damage the tablet. Make sure your hands are dry when handling these tablets. Place the tablet on your tongue right away and let it melt.
- Risperidone can affect your ability to regulate your body temperature.
- If you drink alcohol, talk with your doctor about whether risperidone is safe for you.
- Therefore, before using this product, tell your doctor or pharmacist of all the products you use.
- The plasma protein binding of risperidone is approximately 90%, and that of its major metabolite, 9-hydroxyrisperidone, is 77%.
- A household spoon is not an accurate measuring device and may cause you to take the wrong dose.
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine.
These medicines work on the balance of chemical substances in the brain. If you plan to have children, talk with your doctor before receiving this medicine. Some female patients receiving this medicine have become infertile (unable to have children). Your doctor may need to check your weight on a regular basis while you are receiving this medicine.
Dosing should be modified accordingly in the elderly patients see Use In Specific Populations. CYP 2D6, also called debrisoquin hydroxylase, is the enzyme responsible for metabolism of many neuroleptics, antidepressants, antiarrhythmics, and other drugs. CYP 2D6 is subject to genetic polymorphism (about 6%-8% of Caucasians, and a very low percentage of Asians, have little or no activity and are “poor metabolizers”) and to inhibition by a variety of substrates and some nonsubstrates, notably quinidine.
Clinical monitoring of weight is recommended during treatment. Possible risk factors for leukopenia/neutropenia include pre-existing low white blood cell count (WBC) and history of drug-induced leukopenia/neutropenia. When treating pediatric patients with RISPERDAL for any indication, weight gain should be assessed against that expected with normal growth. Weight gain has been observed with atypical antipsychotic use. Tardive dyskinesia may remit, partially or completely, if antipsychotic treatment is discontinued.
The risk of dizziness and sleepiness may be increased if you drink alcohol while using Uzedy. Tell your healthcare provider if you have or have had any of the following. Uzedy may cause an unwanted erection that is persistent, painful, and that may occur without sexual arousal. Stop using Uzedy and get emergency help right away if you have any of the following symptoms of priapism. Uzedy may cause allergic reactions, which can be serious. Stop using Uzedy and get help right away if you have any of the following symptoms of a serious allergic reaction.